BDBM50084661 4-(4'-Chloro-biphenyl-4-yl)-4-oxo-2-phenylsulfanylmethyl-butyric acid(Bay-12-9566)::CHEMBL261932::Tanomastat

SMILES OC(=O)[C@@H](CSc1ccccc1)CC(=O)c1ccc(cc1)-c1ccc(Cl)cc1

InChI Key InChIKey=JXAGDPXECXQWBC-LJQANCHMSA-N

Data  10 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50084661   

TargetCollagenase 3(Homo sapiens (Human))TBA
LigandPNGBDBM50084661(4-(4'-Chloro-biphenyl-4-yl)-4-oxo-2-phenylsulfanyl...)
Affinity DataKi:  1.47E+3nMAssay Description:Inhibition of MMP-13 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCollagenase 3(Homo sapiens (Human))TBA
LigandPNGBDBM50084661(4-(4'-Chloro-biphenyl-4-yl)-4-oxo-2-phenylsulfanyl...)
Affinity DataKi:  1.47E+3nMAssay Description:Inhibition of matrix metalloprotease-13 (MMP-13).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed